What is the risk associated with long-term use of corticosteroids in surgical patients?

• A. Improved surgical outcomes
• B. Increased patient satisfaction
• C. Impaired wound healing
• D. Decreased sensitivity to pain

Answer: (C)

Long-term use of corticosteroids in surgical patients is associated with impaired wound healing due to their effects on the immune response and tissue repair mechanisms. Corticosteroids are known to suppress inflammation, which is a critical component of the healing process. While inflammation is often viewed negatively, it plays an essential role in the initial stages of wound healing, helping to clear debris and initiate tissue repair.

When corticosteroids are administered over an extended period, they can inhibit various cellular functions, including the activity of fibroblasts and the production of collagen, both of which are crucial for wound closure and integrity. Additionally, corticosteroids can cause vasoconstriction, reducing blood flow to the healing tissue, which further compromises the wound healing process. This scenario can lead to complications such as delayed healing, increased risk of infection, and even wound dehiscence.

The other options do not accurately reflect the risks associated with corticosteroid use in this context. Improved surgical outcomes and increased patient satisfaction are not typically correlated with long-term corticosteroid use, and decreased sensitivity to pain is not a primary concern or documented consequence related to corticosteroid therapy in surgical patients.